Research

Macoupin Research Group (MRG) is an experienced, community-based, private practice, family medicine facility dedicated to conducting outpatient, Phases III, III-B and IV Clinical trials for the pharmaceutical industry. We have a trained, professional healthcare team dedicated to performing the highest quality clinical research. This commitment helps to advance the healthcare options for our patients, and accelerates the new drug development process.

MRG, located 60-minutes east of the St. Louis International Airport in tranquil country surroundings, presents a team of highly trained and dedicated medical professionals including three physicians, three Physician Assistants, and two Clinical Research Coordinators.

MRG's 6,000 square-feet facility has nine examination rooms, a well equipped lab for specimen processing, secured investigational drug storage facility, specimen refrigerators and freezers (-20°C) for lab sample storage, ample space for study material, a state-of-the-art computer network, dedicated space for study coordinators, and a comfortable reception area. Our convenient on-site diagnostic capabilities include:

• Pulmonary function testing
• Electrocardiography
• Ultrasound
• X-ray facilities
• Holter monitoring
• Bone densitometry

Our principal investigators, Sub-investigators and Clinical Research Coordinators are trained in FDA Regulations and ICH God Clinical Practice Guidelines. Our Clinical Research Coordinators are also certified for the shipping of diagnostic specimens and dry ice handling.

To ensure full coverage of our research Subject's needs, MRG has two trained and experienced Clinical Research Coordinators for backup coverage. We maintain high quality and standardization across our operations through established standard operating procedures covering a broad range of topics.

MRG Standard Operating Procedures:

• Standard Operating Procedures For SOPs
• Adverse Event Reporting Procedures
• Clinical Study Operations
• Handling Clinical Trial Test Article
• Communication Documentation
• Coordinator Selection, Qualifications, Responsibilities and Training
• Data Management
• Informed Consent
• Investigator Agreements With Sponsors/CROs
• Investigator and Sub-Investigator Selection, Qualifications, Responsibilities and Training
• Institutional Review Board Approval and Operations For Clinical Studies
• Pre-Study Requirements
• Protocol Handling, Review of Feasibility, and Approval
• Quality Control
• Subject Recruitment Methods
• Regulatory Documentation/Essential Documents
• Sponsor Interactions
• Study Close-Out Activities
• Study Confidentiality
• Federal Food And Drug Administration (FDA) Audits
• Handling Allegations of Misconduct and Fraud
• Disaster Recovery Planning